Research division Life Science and Bioprocesses

Functional Protein Systems/ Biotechnology

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Biomaterials and Healthcare

Here, nanotechnology, surface chemistry and polymer science are combined to develop new high-tech materials for medical applications.

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Life Science and Bioprocesses

Polymeric materials with biological functions

Nature has been developing and optimizing biological systems for millions of years. We use these proven mechanisms in the research division of Life Science and Bioprocesses to expand the range of polymer functionality. Our focus is on integrating new biological functions into polymer materials.  

In the department of Functional Protein Systems/Biotechnology, polymer research is combined with biotechnology in a unique way. Functional biobased building blocks are produced and implemented using chemical, physical and biotech methods. Interactive colloidal systems are also developed.

The department of Biomaterials and Healthcare unites polymer research, nanotechnology and interfacial chemistry to develop new, high-tech materials for medical technology through to application maturity.

Our services

Keratin fibers

  • surface treatment and analytics (Dia-Stron)
  • digestion of keratin waste (fibers, paper)


Biotech processes

  • development and optimization of fermentation processes including product processing
  • development and production of enzymes, structural proteins and protein building blocks
  • biotechnological production of organic monomers (metabolic pathway engineering)
  • biocatalysis
  • material utilization of renewable raw materials


Protein conjugates

  • modification of protein bonding agents
  • channel proteins for membrane applications
     

Self-assembly techniques

  • colloidal building blocks
  • polymeric nanostructures
  • surface and interface-driven assembly
  • functional coatings
     

Development of materials for life science    

  • hydrogels, polymer dispersions
  • »Intelligent« materials for medical applications
  • implants
  • active ingredient systems, drug delivery systems
  • cosmetics
  • microbiology testing

Our research topics

Our activities in the research division of Life Science and Bioprocesses span a wide range of application fields. We develop materials and key substances, for example, for biotechnology, medical products, pharmaceuticals and cosmetics, as well as for environmental- and nanotechnologies.

In addition to the traditional research fields, our research and development concentrates on biomaterials and hydrogels, implants, bioactive surfaces, sensors and biotech processes. Microbiology testing and testing using primary cells and cell lines deepen the scope of our R&D capabilities.

Focus is also placed on the synthesis of polymers and biohybrid materials, the production of ultra-thin membranes and the biofunctionalization of surfaces.

Our developments in biotechnology are implemented on a lab-scale and scaled up to pilot plant-scale. The utilization of renewable raw materials in the production of biopolymers and their use as a fermentation substrate play a key role in this regard.

Our equipment

Fuctional Protein Systems/Biotechnology

  • incubator shakers and CO2-incubator
  • ultra centrifuge
  • cryo vibration mill, ultra-sonic homogenizer
  • centrifugal mill
  • vertical gel electrophoresis systems (1D, 2D), blotting apparatus
  • PCR thermocycler, horizontal gel electrophoresis systems – gel imaging system “ChemiDoc MP“
  • realTime PCR
  • DGGE/SSCP-system
  • UV/VIS-spectrometer and fluorescence-micro plate reader
  • stainless steel bioreactors: 3x 2 liter, 1x 10 liter, 1x 100 liter working volume with exhaust gas analytics and process analytics
  • disc separator for cell harvest
  • high pressure homogenizer for cell disruption
  • filtration device for ultra-, micro- and diafiltration
  • analytical and preparative HPLC system
  • freeze-drying (up to 20 liter scale) and rotary evaporator (10 liter scale)
  • langmuir balance
  • zetasizer
  • atomic force microscope

 

Functional Polymers for Medical Technology

  • modern synthesis laboratories for low-and high-molecular compounds
  • modern methods of molecular analysis of organic substances
  • various methods of molecular weight analytics: size exclusion chromatography (GPC/SEC), cryoscopy, osmotic pressure, vapor pressure osmometry (VPO), ultracentrifuge
  • polyelectrolyte titration, turbidity photometry
  • UV-vis-NiR and FT-IR spectrometer
  • HPLC high performance liquid chromatography coupled with MS
  • thermogravimetry and differential scanning calorimetry (DSC)
  • microscopes (with polarization, darkfield and phase contrast facility stereo incident light, inverse fluorescence and confocal laser scanning microscope)
  • photomicrograph and digital image analysis
  • dynamic light scattering
  • surface tension (tensiometers, spinning drop)
  • rheometer (rotation, oscillation, interfacial rheology)
  • precision density measurement
  • ellipsometer
  • surface plasmon resonance spectrometer (SPR)
  • contact angle measurement
  • spin and dipcoater
  • determination of the minimum film forming temperature (MFT)
  • steam sterilizers, autoclaves
  • ultra-high performance liquid chromatography (UHPLC) with MS coupling
  • gas chromatography with MS coupling

Alexander Böker

Contact Press / Media

Prof. Dr. Alexander Böker

Head of department | Functional Protein Systems/Biotechnology

Fraunhofer IAP
Geiselbergstraße 69
14476 Potsdam-Golm

Phone +49 331 568-1112

Joachim Storsberg

Contact Press / Media

Dr. Joachim Storsberg

Head of department | Biomaterials and Healthcare

Geiselbergstraße 69
14476 Potsdam-Golm

Phone +49 331 568-1321

Life Science and Bioprocesses

Functional Protein Systems/Biotechnology

Biomaterials and Healthcare