© Fraunhofer IAP
© Fraunhofer IAP

Biomaterials and Healthcare

© Fraunhofer IAP
© Fraunhofer IAP

Quickly identifying tumors by using antibodies

Antibodies combat viruses and bacteria. They also attach themselves to cancer cells – in a typical, characteristic way. Fraunhofer scientists are using this property to detect cancer cells in tissue samples. Such rapid tests can already be applied by surgeons during operations – within a few minutes and without expensive equipment.

more info

Biomaterials and Healthcare

Biomaterials for medical engineering

The department Biomaterials and Healthcare develops biomaterials for diverse applications. Nanotechnology, surface chemistry and polymer science are combined to develop new high-tech materials for the medical engineering ready for use, such as implants and drug systems. Research and development take place in an interdisciplinary team.

Press releases

Our services

  • development and production of implants, in particular for ophthalmology
  • development of bioactive surfaces for use in implants
  • complex biochemical modifications
  • development of polymer-bound antibody systems
  • binding of proteins to polymer surfaces
  • surface modifications/alterations

  • microbiological research and development
  • microbiological safety laboratory
  • official approval according to § 44 IfSG
  • investigations with pathogenic viruses, bacteria and fungi

  • examination of genotoxicity (Ames test)
  • identification of mutagens
  • wound healing assay
  • toxicity and drug screening with primary cell assays

  • in vitro analysis
  • optical microscopy (confocal laser scanning, fluorescence, etc.)
  • optical spectroscopy
  • biocompatibility studies
    • chemical
    • physically
    • biological
  • cytotoxicity determination
  • in vitro studies with cell cultures
  • studies on explants / expert reports
  • in vitro studies with human primary cells
  • in vitro studies with human tumor cells
  • studies in vitro with viruses
  • testing of pharmacological inhibitors with transfected cell lines

Our research topics

  • interdisciplinary research and development in the medical field
  • development of implants: intraocular lenses, artificial cornea (keratoprosthesis)
  • hydrogel-based biomaterials, contact lenses
  • implants with tissue-specific properties
  • iInteractions between biological tissues and biomaterials
  • development of methods for tailored control of cell-binding and cell-repulsive properties of biomaterials
  • development of medical devices of classes I, II and III

Our equipment

  • modern synthesis laboratories for low-and high-molecular compounds
  • modern methods of molecular analysis of organic substances
  • various methods of molecular weight analytics: size exclusion chromatography (GPC/SEC), cryoscopy, osmotic pressure, vapor pressure osmometry (VPO), ultracentrifuge
  • polyelectrolyte titration, turbidity photometry
  • UV-vis-NiR and FT-IR spectrometer
  • HPLC high performance liquid chromatography coupled with MS
  • thermogravimetry and differential scanning calorimetry (DSC)
  • microscopes (with polarization, darkfield and phase contrast facility stereo incident light, inverse fluorescence and confocal laser scanning microscope)
  • photomicrograph and digital image analysis
  • dynamic light scattering
  • surface tension (tensiometers, spinning drop)
  • rheometer (rotation, oscillation, interfacial rheology)
  • precision density measurement
  • ellipsometer
  • surface plasmon resonance spectrometer (SPR)
  • contact angle measurement
  • spin and dipcoater
  • determination of the minimum film forming temperature (MFT)
  • steam sterilizers, autoclaves
  • ultra-high performance liquid chromatography (UHPLC) with MS coupling
  • gas chromatography with MS coupling


Künstliche Hornhaut für Ultima-ratio-Patienten
J. Storsberg, G. I. W. Duncker, Ch. Schmidt, K. Kobuch, A. Meßner, S. Sel
Z. prakt. Augenheilkd. 34: S. 107 – 111, Potsdam, Halle, München, Sankt Augustin, Heidelberg (2013)

Nanomaterials -Tools, Technology and Methodology of Nanotechnology Based Biomedical Systems for Diagnostics and Therapy
C. Schmidt, J. Storsberg
Biomedicines, 3/3, 203-223, pp. 2227-9059 (2015)

Artificial Cornea for ultima ratio patients
J. Storsberg, G.I.W. Duncker, C. Schmidt, K. Kobuch, A. Meßner, S.Sel
Zeitschrift für praktische Augenheilkunde, 34, pp. 107-111 (2013)

Anti-Ageing Creams, Ingedients and their Affects Against Early Skin Ageing
L. Vetter, M. W. Laughton, C. Schmidt, J. Storsberg
SOFW-Journal, 140/11, pp. 34-39 (2014)